Gezim is heading the Global Pharmacometrics unit, and also is a site head of Translational and Early Clinical Development at Takeda. Gezim is responsible for identifying, developing and utilizing different analytical/Modelling, Systems Pharmacology technologies and personalized medicine approaches that allow assessment of Disease, drug-exposure and biomarker response relationship in different therapeutic areas within the early and late clinical development. Before joining Takeda Pharmaceuticals Gezim headed the division of PKPD and Biomarker Sciences at Nycomed and was responsible for defining the PKPD and Biomarker strategies and development plans including the definition of the fit for purpose tailored Biomarker development, Clinical Pharmacokinetics and Modelling and simulation strategies in the translational space and for proof of concepts studies. Gezim has also headed the department of Clinical Pharmacokinetics and Pharmacometrics at Altana Pharma AG and continued to do the same at Nycomed GmbH before he took additional responsibilities in incorporating the biomarker research into the Translational Development.